At Health Destination, we pride ourselves on being the leading provider of top-notch lab tests, cutting-edge diagnostic services, and convenient [ **home sample collections**](https://healthdestination.in/) right here in Gurgaon. Our mission is simple: to prioritize your health, offering accurate and reliable reports while ensuring a seamless experience from start to finish.

**Comprehensive Range of Lab Tests**

Our commitment to accuracy drives us to offer a diverse array of tests that cover various health aspects. Whether for routine checkups, specific health concerns, or specialized tests, our state-of-the-art facilities guarantee precise results.

**Convenience Meets Precision**

At **Health Destination**, we've made accessing and managing your health reports incredibly easy. Our user-friendly platform allows you to effortlessly **book lab tests**, upload reports, and choose personalized health packages tailored to your unique needs. Expect nothing less than reliable and accurate health reports.

**Hassle-Free Home Sample Collection**

Opt for our free home sample collection service for added convenience. Simply [**book your test online**](https://healthdestination.in/test-and-package), and our certified professionals will collect samples at your preferred location. Your health journey starts here.

**Join the Health Journey**

Your health matters, whether you're in Gurgaon or nearby cities. Our dedication to quality healthcare services extends beyond **Gurgaon**, covering neighboring areas. Our certified technicians are equipped to serve not only in Gurgaon but also in nearby regions, ensuring quality healthcare accessible to all.

_**Ready to prioritize your health? Book your lab test, schedule a home sample collection, or visit our lab in Gurgaon today!**_

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Contact Details:

Address: Health Destination, Golf Course Road, Sector 54, Gurugram, Haryana, India
Phone: +91 9310277077
Email: info@healthdestination.in
Website: https://healthdestination.in/











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A volunteer in New Zealand has become the first person to undergo DNA editing in order to lower their blood cholesterol, a step that may foreshadow wide use of the technology to prevent heart attacks.

The experiment, part of a clinical trial by the US biotechnology company Verve Therapeutics, involved injecting a version of the gene-editing tool CRISPR in order to modify a single letter of DNA in the patient’s liver cells.

According to the company, that tiny edit should be enough to permanently lower a person’s levels of “bad” LDL cholesterol, the fatty molecule that causes arteries to clog and harden with time.

The patient in New Zealand had an inherited risk for extra-high cholesterol and was already suffering from heart disease. However, the company believes the same technique could eventually be used on millions of people in order to prevent cardiovascular disease.

“If this works and is safe, this is the answer to heart attack—this is the cure,” says Sekar Kathiresan, a gene researcher who started Verve three years ago and is the company’s CEO.

It’s been 10 years since scientists developed CRISPR, a technology for making targeted changes to the DNA in cells, but until now the method has been tried only on people suffering from rare diseases like sickle-cell anemia, and only as part of exploratory trials.

If Verve’s experiment works, it could signal far wider use of gene editing to prevent common conditions. Large swaths of the world’s population have LDL that is too high, but many people can’t get it under control. Worldwide, more people die of atherosclerotic cardiovascular disease than from anything else.

 “Of all the different genome editing ongoing on the clinic, this one could have the most profound impact because of the number of people who could benefit,” says Eric Topol, a cardiologist and researcher at Scripps Research.

Some doctors believe lowering LDL aggressively, and keeping it low throughout life, could essentially prevent people from dying of cardiovascular disease. That is the view of Eugene Braunwald, a physician at Brigham & Women’s Hospital in Boston who is also an advisor to Verve.

“The lower the LDL, the better,” says Braunwald. “You can’t have too low an LDL. The problem is how do you get it down?”

A strict diet, like one where you avoid eggs, meat, and even olive oil, can help. But few people succeed in sticking to it. Then come statins, the most widely prescribed medicine in the US. These pills can cut a person’s LDL in half, but some can’t handle the side effects, and some find even taking a once-a-day pill hard to manage.

Some newer biotech drugs involve injections twice a month, or even just twice a year. These drugs are quite powerful, and Braunwald recently speculated what would occur if they were given widely as a public health intervention, not unlike an annual flu vaccine. “I calculate it if you give it starting at age 30, you will live to 100 without coronary artery disease,” he says.

However, those drugs aren’t yet widely used. They remain costly, are still inconvenient, and insurers balk at paying. “So gene editing is the big stick, because it’s one and done. You don't ever have to come back,” says Braunwald. “It’s a very big deal, because atherosclerotic cardiovascular disease is the most common cause of death in the industrialized world, and LDL is the primary reason.”

In New Zealand, where Verve’s clinical trial is taking place, doctors will give the gene treatment to 40 people who have an inherited form of high cholesterol known as familial hypercholesterolemia, or FH. People with FH can have cholesterol readings twice the average, even as children. Many learn they have a problem only when they get hit with a heart attack, often at a young age.

The study also marks an early use of base editing, a novel adaptation of CRISPR that was first developed in 2016. Unlike traditional CRISPR, which cuts a gene, base editing substitutes a single letter of DNA for another.

The gene Verve is editing is called PCSK9. It has a big role in maintaining LDL levels and the company says its treatment will turn the gene off by introducing a one-letter misspelling.

Before starting Verve, Kathiresan was a geneticist working at the Broad Institute in Cambridge, Massachusetts, looking for inherited causes of heart disease. He started Verve after his brother, Senthil, was struck down suddenly by a heart attack; base editing, he thought, could be a way to prevent such tragedies.

One reason Verve’s base-editing technique is moving fast is that the technology is substantially similar to mRNA vaccines for covid-19. Just like the vaccines, the treatment consists of genetic instructions wrapped in a nanoparticle, which ferries everything into a cell.

While the vaccine instructs cells to make a component of the SARS-CoV-2 virus, the particles in Verve’s treatment carry RNA directions for a cell to assemble and aim a base-editing protein, which then modifies that cell’s copy of PCSK9, introducing the tiny mistake. 

In experiments on monkeys, Verve found that the treatment lowered bad cholesterol by 60%. The effect has lasted more than a year in the animals and could well be permanent. 

The human experiment could entail some risk. Nanoparticles are somewhat toxic, and there have been reports of side effects, like muscle pain, in people taking other drugs to lower PCSK9. And whereas treatment with ordinary drugs can be discontinued if problems come up, there’s as yet no plan to undo gene editing once it’s performed.

So far, the few gene therapies on the market all cost hundreds of thousands of dollars—even as much as $2 million. But Verve’s should be much cheaper, especially if used widely. One reason is that whereas other gene therapies use specially prepared viruses to carry genes, nanoparticles are made in a chemical process that’s more practical to scale up.

“The pandemic and the emergent need for vaccines [created] large-scale manufacturing capacity,” says Kiran Musunuru, a gene-editing expert at the University of Pennsylvania who cofounded Verve.  That capacity “can be easily repurposed for genetic therapy,” he says, and “of course, abundant capacity means reduced prices.”

Musunuru says people are even thinking about “booster shots” in case the first round of gene editing isn’t complete, or in order to knock out other cholesterol genes and deepen the effect on LDL.

It’s a stroke of luck for Verve’s founders that the main cause of death in the world is also the first common problem that gene editing can address. Kathiresan, who takes a statin to keep his LDL low, says he thinks gene editing for cholesterol has the potential to be a life-extension treatment.

“The number one cause of mortality in the world is heart attack,” he says. "If you are going to give a medicine that makes you avoid a heart attack, people are going to live longer.”

In a first, a patient in New Zealand has undergone gene-editing to lower their cholesterol. It could be the beginning of new era in disease prevention.

Gene Sequencing - A sneak peek to your body composition

T3. T4, TSH commonly bucketed under Thyroid Profile by diagnostic companies. Thyroid tests help health care professionals diagnose thyroid diseases such as

- hyperthyroidism—when thyroid hormone levels are too high
- Graves’ disease, the most common cause of hyperthyroidism
- hypothyroidism—when thyroid hormones levels are too low
- Hashimoto’s disease, of the most common cause of hypothyroidism
- thyroid nodules and thyroid cancer

T3. T4, TSH commonly bucketed under Thyroid Profile by diagnostic companies. Thyroid tests help health care professionals diagnose thyroid diseases such as


Thyroid Tests

World Cancer Day: Feb 4th

Anemia is a common blood disorder that affects millions of people worldwide. At Health Destination Lab, we provide a variety of diagnostic testing services to help diagnose anemia and other blood disorders. In this blog post, we'll take a closer look at anemia, including its symptoms, causes, and the diagnostic testing services we offer at Health Destination Lab.

**Symptoms of Anemia:**

The symptoms of anemia can vary depending on the severity and underlying cause of the condition. Some common symptoms of anemia include:

- Fatigue
- Weakness
- Shortness of breath
- Pale skin
- Chest pain
- Dizziness or lightheadedness
- Cold hands and feet
- Headaches
- Irregular heartbeat

If you're experiencing any of these symptoms, it's important to see a healthcare provider for a proper diagnosis and treatment.

**Causes of Anemia:**

There are many different causes of anemia, including:
- **Iron deficiency:** This is the most common cause of anemia. Iron is needed to make hemoglobin, so if your body doesn't have enough iron, you may develop anemia.
- **Vitamin deficiency:** Deficiencies in vitamin B12, folate, and vitamin C can lead to anemia.
- **Chronic diseases:** Chronic kidney disease, cancer, HIV/AIDS, and other chronic diseases can increase your risk of developing anemia.
- **Inherited conditions:** Sickle cell anemia, thalassemia, and other inherited conditions can cause anemia.
- **Pregnancy:** Anemia is common during pregnancy due to increased blood volume and  increased demands for iron.

**Diagnostic Testing for Anemia at Health Destination Lab:**

If you're experiencing symptoms of anemia, Health Destination Lab can provide diagnostic testing to determine the underlying cause. We offer a variety of tests that can diagnose anemia and other blood disorders, including:

- **Complete blood count (CBC):** This test measures the number of red blood cells, white blood cells, and platelets in your blood. It can help identify anemia and other blood disorders.
- **Reticulocyte count:** This test measures the number of immature red blood cells in your blood. It can help determine if your body is producing enough red blood cells.
- **Peripheral blood smear:** This test involves examining a sample of your blood under a microscope to look for abnormalities in the shape, size, and color of your red blood cells.
- **Iron and vitamin tests:** These tests measure the levels of iron, vitamin B12, folate, and other vitamins in your blood. They can help determine if a deficiency is causing your anemia.

If anemia is diagnosed, treatment may depend on the underlying cause. Treatment options may include iron supplements, vitamin supplements, blood transfusions, or other medications.

In conclusion, anemia is a common blood disorder that can cause a wide range of symptoms. If you're experiencing any symptoms of anemia, Health Destination Lab can provide the diagnostic testing services you need to get a proper diagnosis and treatment. Contact us today to schedule an appointment and get the testing you need to take control of your health.

Anemia is a common blood disorder that affects millions of people worldwide. At Health Destination Lab, we provide a variety of diagnostic testing services to help diagnose anemia and other blood disorders.

Anemia: Symptoms, Causes, and Diagnostic Testing at HD Labs

National Endometriosis Awareness Week is vital for raising awareness about a chronic and often misdiagnosed condition affecting millions of women worldwide. The goal is to educate the public and healthcare professionals about the symptoms, diagnosis, and treatment options for endometriosis. This year, health destination is proud to support National Endometriosis Awareness Week by highlighting the importance of early detection and appropriate care for those living with endometriosis.

Endometriosis is a condition where tissue similar to the endometrial lining of the uterus grows outside of the uterus, causing chronic pain, heavy bleeding, and infertility. Despite affecting an estimated 176 million women worldwide, endometriosis often goes undiagnosed for several years due to a lack of awareness and understanding of the symptoms.

Common symptoms of endometriosis include painful periods, pain during intercourse, and fertility problems. Other symptoms include fatigue, abdominal bloating, and gastrointestinal issues. Endometriosis can be difficult to diagnose as its symptoms can mimic those of other conditions, leading to a delay in treatment. Health Destination Lab offers a wide range of resources to help women understand the symptoms of endometriosis and seek proper medical care.

Diagnosis of endometriosis is typically made through laparoscopic surgery, where a doctor will remove tissue samples for biopsy. Treatment options for endometriosis vary depending on the severity of the disease but can include medications to relieve pain, hormonal treatments to reduce the growth of endometrial tissue, and in severe cases, surgery to remove the affected tissue.

Conclusion:

Endometriosis is a complex condition that affects millions of women worldwide, but due to its lack of visibility and understanding, many women suffer in silence. Raising awareness about the symptoms, diagnosis, and treatment options for endometriosis is crucial for improving the lives of women who suffer from this disease. At Health Destination, we believe in empowering women with the knowledge they need to take control of their health. If you or someone you know is experiencing symptoms of endometriosis, it is important to speak with a healthcare provider for a proper diagnosis and treatment plan.

This article provides information about endometriosis, including its symptoms, diagnosis, and treatment options. By raising awareness about this condition, we can help improve the lives of the millions of women who suffer from it. At Health Destination, our goal is to provide women with the resources they need to understand and manage this disease.

National Endometriosis Awareness Week is vital for raising awareness about a chronic and often misdiagnosed condition affecting millions of women worldwide. The goal is to educate the public and healthcare professionals about the symptoms,

Endometriosis:Understanding the Silent Disease-Health Destination

When you become a parent, your baby's health and well-being become your top priority. One important step you can take to ensure your baby's long-term health is to have them undergo newborn screening. At Health Destination Lab, we offer comprehensive newborn screening services that can detect a range of genetic and metabolic disorders, including phenylketonuria (PKU), hypothyroidism, galactosemia, sickle cell disease, and cystic fibrosis.

Newborn screening is a simple blood test that is done within the first few days of life. It can identify potentially life-threatening conditions before symptoms even appear, giving parents and medical professionals the opportunity to take early intervention measures. The quick and painless test involves taking a small sample of blood from your baby's heel.

At Health Destination Lab, we understand the importance of newborn screening and are committed to providing the highest level of care to you and your baby. Our state-of-the-art laboratory uses the latest technology and testing methods to provide accurate results for a range of conditions, including:

**Phenylketonuria (PKU):** A rare genetic disorder that affects the body's ability to break down the amino acid phenylalanine. If left untreated, PKU can lead to intellectual disabilities and other serious health problems.

**Hypothyroidism:** A condition in which the thyroid gland does not produce enough thyroid hormone. If left untreated, hypothyroidism can lead to growth and developmental delays.

**Galactosemia:** A rare genetic disorder that affects the body's ability to break down the sugar galactose. If left untreated, galactosemia can lead to intellectual disabilities and other serious health problems.

**Sickle cell disease:** A group of inherited blood disorders that affect the production of hemoglobin, the protein that carries oxygen in the blood. If left untreated, sickle cell disease can cause a range of health problems, including anemia, infections, and chronic pain.

**Cystic fibrosis:** A genetic disorder that affects the lungs, pancreas, and other organs. If left untreated, cystic fibrosis can lead to a range of health problems, including respiratory infections and digestive issues.

Our team of experienced professionals will work with you and your pediatrician to develop a personalized treatment plan if any health conditions are detected.

It's important to note that early detection is key to managing genetic and metabolic disorders. If your baby's newborn screening results come back positive for any condition, it's important to work with your pediatrician and our team at Health Destination Lab to develop a treatment plan that is tailored to your baby's specific needs.

Newborn screening is a critical aspect of ensuring your baby's long-term health. By detecting potential health conditions early, you can take proactive measures to manage them and prevent complications. At Health Destination Lab, we are proud to offer this essential service to parents in our community, and we encourage all parents to take advantage of this opportunity to protect their baby's health.

If you have any questions about newborn screening or would like to schedule a test for your baby, please contact Health Destination Lab today. Remember, early detection and treatment can make all the difference in your baby's health and well-being.

When you become a parent, your baby's health and well-being become your top priority. One important step you can take to ensure your baby's long-term health is to have them undergo...

Health Destination: Providing Essential Newborn Screening Tests

Colorectal cancer is a serious disease that affects many people each year. According to the American Cancer Society, Colorectal Cancer is the third most common cancer diagnosed in both men and women in the United States. The good news is that Colorectal Cancer is preventable and treatable, especially when detected early through regular screening. In this blog post, we'll explore the importance of colorectal cancer screening and how you can take action to protect your health with a screening at HD Labs.

## Why is Colorectal Cancer Screening Important?

Colorectal cancer often develops slowly over time, and symptoms may not appear until cancer has advanced. This is why screening for colorectal cancer is so important. Regular screening can detect the disease at an early stage, when it is most treatable. Screening can also help prevent colorectal cancer by detecting and removing polyps before they become cancerous.

What are the Screening Options?

There are several screening options available for colorectal cancer, including:

Fecal Occult Blood Test (FOBT)

Stool DNA Test (FIT-DNA)

Flexible Sigmoidoscopy

Colonoscopy

Each screening option has its own benefits and drawbacks, so it's important to talk to your doctor about which test is right for you. Generally, screening is recommended for people at average risk starting at age 45, and earlier for those with certain risk factors.

How to Schedule Your Colorectal Cancer Screening at HD Labs

Don't wait any longer if you're due for a colorectal cancer screening. Schedule your test today at HD Labs, one of the leading providers of high-quality and affordable health screening services. Our experienced staff will guide you through the screening process and answer any questions you may have.

To schedule your screening at HD Labs, simply visit our website ([https://healthdestination.in/](https://healthdestination.in/) )  or call us at \[9310277077\]. Don't wait, take control of your health and protect yourself from colorectal cancer today.

Colorectal cancer is a serious disease that affects many people each year. According to the American Cancer Society, Colorectal Cancer is the third most common cancer diagnosed in...

Schedule Your Colorectal Cancer Screening At HD Labs

 Tuberculosis (TB) remains one of the top 10 causes of death worldwide, with millions of people affected each year. Despite being a preventable and curable disease, TB continues to ravage communities and cause significant economic and social burdens. At the Health Destination Lab, we believe that we can end TB once and for all with innovative solutions and the right investments in research, technology, and health systems.

Prevention: One of the most effective ways to end TB is through prevention. This includes strategies such as vaccination, screening, and active case finding. The Health Destination Lab is supporting innovative approaches to TB prevention, such as the development of new vaccines and rapid diagnostic tests that can detect TB in its early stages.

Treatment: For those who contract TB, early diagnosis and effective treatment are essential. The Health Destination Lab is supporting the development of new and more effective TB treatments, including shorter and more patient-friendly drug regimens that can improve adherence and reduce the risk of drug resistance.

Research: Continued investment in TB research is critical to finding new solutions and improving existing ones. The Health Destination Lab is working with partners around the world to support cutting-edge research in areas such as TB vaccines, biomarkers, and drug development.

Partnerships: Ending TB requires a collaborative effort from governments, civil society, the private sector, and other stakeholders. The Health Destination Lab is proud to be part of the global movement to end TB, and we are committed to working with our partners to advocate for increased funding, better policies, and more effective interventions.

At the Health Destination Lab, we believe that we can create a TB-free world with innovative solutions and the right investments in research, technology, and health systems. We are committed to supporting cutting-edge research, advocacy, and partnerships that can help us achieve this goal. Join us in our mission to create a healthier and more equitable world, free from the burden of TB.

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